by Wim Mees | May 10, 2023 | Team events
Recently we enjoyed some delicious and freshly shaken, but not stirred, (m)(c)ocktails with the myNEO team. It was great catching up with everyone. #workhardplayhardThanks Deloitte for this great reward! #fast50 Enjoy the pictures !by Wim Mees | Feb 13, 2023 | Press release
Odimma Therapeutics and myNEO Therapeutics will partner to identify personalized targets for clinical development of DNA-based cancer vaccine therapy. The myNEO Therapeutics project team is excited to have Odimma as our newest partner, and to be able to enter the...The process starts with the collection of both patient blood and a tumor biopsy.
Whole-Genome Sequencing data from matched tumor and normal DNA is required for each patient.
Following alignment of these reads to the genome, somatic gene alterations in the tumor genome are detected using a collection of algorithms called 'neoX'.
Next, these somatic gene alterations are translated in-silico to obtain the tumor-specific peptides
In a last step, the peptides are prioritized using an immunogenicity predictor (neoIM) and two presentation predictors (neoMS and MHCrank).