by Wim Mees | Apr 7, 2021 | Press release, News
Fighting Cancer with Personalized Vaccines: ONCODNA and myNEO Therapeutics collaboration OncoDNA, a company specializing in precision medicine, and myNEO Therapeutics, an AI-driven company revolutionizing neoantigen discovery within immuno-oncology, are thrilled to...by Wim Mees | Oct 21, 2020 | Team events
This week the myNEO team had multiple reasons to celebrate! Bruno his promotion to CTO 1 year working anniversary of Lore and Lien End of the internship of Claudia 500+ followers on LinkedIn We had a great night over drinks and some...by Wim Mees | Jun 10, 2020 | Team events
Yesterday myNEO organised its first teambuilding activity after the lockdown. We all worked remotely during the lockdown so it was nice to all be together again as a team. We had some drinks, ate a tasty diner and played some board games to finish off the...The process starts with the collection of both patient blood and a tumor biopsy.
Whole-Genome Sequencing data from matched tumor and normal DNA is required for each patient.
Following alignment of these reads to the genome, somatic gene alterations in the tumor genome are detected using a collection of algorithms called 'neoX'.
Next, these somatic gene alterations are translated in-silico to obtain the tumor-specific peptides
In a last step, the peptides are prioritized using an immunogenicity predictor (neoIM) and two presentation predictors (neoMS and MHCrank).